Alpha-glucosidase inhibitors

Rosamultic acid
Catalog No: CFN92608

Rosamultic acid is a class of triterpenes with α-glucosidase inhibitory activity.

Isoderrone
Catalog No: CFN92794

Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, suggests that it may be a new drug for treatment of type 2 diabetes.

Irigenin
Catalog No: CFN93276

Irigenin, an α-glucosidase inhibitor, which has anti-inflammatory, anti-cancer, and anti-metastatic effects. Irigenin can inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins and mRNAs without an appreciable cytotoxic effect. Irigenin displays moderate activity as inducers of NAD(P)H:quinone reductase (QR) in cultured mouse Hepa 1c1c7 cells.

Gitogenin
Catalog No: CFN93779

Gitogenin is a novel selective inhibitor of UGT1A4, it is also an inhibitor of enzyme α-glucosidase with IC50 values of 37.2±0.18 uM.Gitogenin shows moderate stimulation of release activity on growth hormone from rat pituitary cells.

3,7-Di-O-methylquercetin
Catalog No: CFN96221

3,7-Di-O-methylquercetin shows α-glucosidase inhibition.